GPI MEDICAL MARIJUANA CLINIC & RESOURCES
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Lithium

Action to be taken: No action needed

Rationale:Lithium has a low therapeutic index and is renally excreted and hence has renally-mediated but not hepatically-mediated drug-drug interactions. Since cannabis is extensively metabolized by CYP enzymes its not expected for cannabis to interact with lithium
References
  1. Ketter TA, Frye MA, Corá-Locatelli G, Kimbrell TA, Post RM. Metabolism and Excretion of Mood Stabilizers and New Anticonvulsants. Cellular and Molecular Neurobiology. 1999;19:511-532.
  2. Watanabe K, Yamaori S, Funahashi T, et al. Cytochrome P450 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes. Life Sci. 2007;80:1415-1419.

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Last Updated: May 2018.
  • Home
  • Company
    • About Us
    • Services
  • Support
    • For Patients >
      • Qualifying Conditions
      • Cost of Visit
      • How Marijuana Works
      • Side Effects and Safety
      • Approved Formulations and Dosing
      • Dispensaries
      • Caregivers
      • How to Register ?
      • FAQ
    • For Clinicians >
      • Research
      • Drug Interactions
  • Contact